Hess Hollow is an unofficially named tributary of Coles Creek in Columbia County, Pennsylvania, in the United States.

Hess Hollow begins in a pond in Sugarloaf Township, just south of Central Mountain.

[1] Hess Hollow joins Coles Creek 2.06 miles (3.32 km) upstream of its mouth.

[3] The area in the vicinity of the stream mainly consists of forested wetlands and open graminoid marshes.

[7] The Columbia County Natural Areas Inventory recommends selective cutting and increased deer hunting in the vicinity of Hess Hollow.

[8] Hess Hollow is listed as a "locally significant site" on the Columbia County Natural Areas Inventory.

These include many species of sedges and ferns, and also buttercups, club mosses, false hellebores, Indian cucumbers, huckleberries, jewelweed, raspberries, sphagnum moss, trillium, wood nettles, and numerous others.

These include two warblers, the black-capped chickadee, the blue-headed vireo, the common yellowthroat, the ovenbird, the veery, and the wood thrush.