Hexaplex is a genus of medium-sized to large sea snails, marine gastropod mollusks in the subfamily muracinae of the family Muricidae, the murex shells or rock snails.

[1] This genus is known in the fossil record from the Paleocene to the Quaternary period (age range: from 61.7 to 0.012 million years ago.).

Fossil shells within this genus have been found all over the world.

[2] This genus includes shells in the family Muricidae that are solid and globose.

Species within the genus Hexaplex include :[1] Extinct species within the genus Hexaplex include:[2]