Homalocantha anatomica (common name: "Pele's Murex" or "Anatomical Murex") is a species of sea snail, a marine gastropod mollusk in the family Muricidae, the murex snails or rock snails.

[1][2] This species occurs in the Red Sea and throughout the Indo-Western Pacific, from Japan, Philippines and Fiji to the Hawaiian Islands.

[3] These shells are solid, whitish in color, sometimes tinted with yellow or red and moderately light in weight, with five to six varices per whorl.

Columella is smooth and siphonal canal is moderately long.

[4] These sea snails feed primarily on boring mussels in reef rocks.