[3] Both the station and the eponymous hamlet were established by Valentine Hicks – the son of an abolitionist preacher who also briefly served as President of the LIRR.

[3] In 1841, the Main Line was extended east from Hicksville to Farmingdale, after a delay caused by the depression that had begun with the Panic of 1837.

[3] In 1854, the station gained a line known as the Hicksville and Syosset Railroad that later became the Port Jefferson Branch of the LIRR.

[10] The $121 million renovation included replacing station platforms, escalators, elevators, waiting rooms, canopies, and lighting.

East of the station, the Port Jefferson Branch splits from the Main Line at DIVIDE Interlocking.

In January 2025, it was officially announced announced that a new Long Island branch of Amtrak's Northeast Regional, running east to Ronkonkoma via the LIRR's Main Line, would serve the Hicksville Station, with an intermediate stop at Jamaica east of Penn Station.