[5] In 1927 she recorded Donald Heywood's "Mango Lane" and "Susanne", singing a duet with Dan Michaels as the composer accompanied them on the piano.
[6][7][8] In March 1927, she appeared opposite Berlena Banks and Jesse Shipp in the Negro musical comedy Lucky Sambo at the La Salle Theatre in Chicago.
[10] Perleno, along with Blanche Calloway, Anna Freeman, Byron Jones, Lew Keene and Evelyn Keys performed in the 1928 show Keep Shufflin' by Miller & Lyles at the Erlanger Theater, Chicago.
[12][13][14] In April 1929, Perleno appeared in the ensemble for Messin' Around,[15] and in June, at the Royale Theatre, she had a minor role as Sheila Nesbit in the play Bamboola.
[20] In April 1937, she appeared supporting Ella Fitzgerald and the Chick Webb Orchestra during their one-week engagement at the Apollo Theater in New York City.