Her famous films include Ezz El-Dine Zulficar's Return My Heart (Rodda Qalbi) with Shoukry Sarhan, Mariam Fakhr Eddine and Salah Zulfikar in 1957, Ibn Hamidu with Ismail Yassine in 1957.

She was cast by Youssef Chahine in the 1958 film Cairo Station (The Iron Gate / Bab El Hadid) alongside Farid Shawki.

She also co-starred in Salah Abu Seif's La Anam (Sleepless) with Faten Hamama, Omar Sharif, and Rushdy Abaza in 1958, Sira' fi al-Nil (Struggle in the Nile) with Omar Sharif and Rushdy Abaza in 1959, and Chafika el Koptia (Chafika the Coptic Girl) in 1963, where she played the role of a Coptic Orthodox nun.

[16] She was married twice, once to Hassan Reda, a film director and father of her only daughter, Passant,[clarification needed] then to Dr. Mohammad Fayaad, a gynecologist.

"I did it for the love of my life, my prince, Dr. Fayaad," she added, referring to her second husband Mohammed Fayyad, whom she was married to for more than 50 years.Rostom was overprotective of her daughter Passant due to worry about the stigma associated with artists’ children lacking parental supervision.