He graduated with a Bachelor of Arts degree from the Interamerican University of Puerto Rico in May 1937.
In 1963 he traveled to Africa as president of the International Arbitration Commission appointed by the International Confederation of Free Organizations (ICFTU) and the Inter-American Organization of Workers (ILO) to resolve disputes and conflicts between the Workers' Federations of Northern and Southern Rhodesia.
He was buried at Cementerio Historico Barrio La Pratt in Humacao, Puerto Rico.
The main building of the Interamerican University of Puerto Rico School of Law was named after Hipólito Marcano.
Part of state road PR 3 in Humacao was named after Hipólito Marcano.