Hisa Nagano (1865 – April 8, 1901) was a Japanese nurse and medical student in Chicago.

In 1892, Nagano and another woman, Natsu Sakaki, went to Chicago under the care of American temperance activists, to study at the Clara Barton Training School for Nurses.

[4] "She is so happy, so deft, winsome, faithful, and full of cheery courage that we all love her," explained the hospital's superintendent in 1897.

She enrolled in the College of Physicians and Surgeons,[6] and worked as a nurse in the city while pursuing her medical training.

[7] Concerned for the effects of overwork and a harsh winter climate, the Japanese consul in Chicago Toshiro Fujita helped Nagano return to Japan to recover her health.