Hit-Girl is a creator-owned comic book sequel series to Kick-Ass: The Dave Lizewski Years, created by Mark Millar and illustrated by John Romita Jr., part of the Kick-Ass franchise and set in the Millarworld.

The title, featuring a successive change of writers and artists for each four-issue story arc, follows Mindy McCready / Hit-Girl leaving the United States to carry on her fight for justice on a worldwide scale, depicting events mentioned in the epilogue of Book Four of The Dave Lizewski Years.

The first issue of Kick-Ass vs. Hit-Girl, a five-issue crossover between Hit-Girl and the supervillainous Patience Lee incarnation of Kick-Ass (written by Steve Niles, art by Marcelo Frusin), was published on November 11, 2020.

[4][5] The series concluded with the release of the fifth issue on April 11, 2021,[6] and was collected as the fourth volume of Kick-Ass – The New Girl.

[7] In January 2019, Kevin Smith expressed interest in Hit-Girl in Hollywood receiving a film adaptation, with "a woman [being] in charge" of production.