It is around 10 kilometres (6.2 mi) from the Adelaide central business district.

Holden Hill is in both the City of Port Adelaide Enfield and City of Tea Tree Gully local government areas, and is in both the South Australian House of Assembly electoral districts of Florey and Torrens.

The road ran through land owned by Mr R. Halden who was a fan of Holden vehicles after 1935.

The Torrens Linear Park cycle path is close to Holden Hill and is easily accessible.

The former bicyclee frame manufacturer, Ciombola, had a factory in Holden Hill.