Holhol (Somali: Hollholl, Arabic: حلحول) is a town in the Ali Sabieh Region of Djibouti.

It is located 44 kilometres (27 miles) south-west of the capital Djibouti City, at an altitude of 450 metres (1,476 feet) above sea level.

The Holhol area has been inhabited since ancient times with nomadics sometimes stopping here for water on the way to the town of Zeila and Harar across the Horn of Africa.

and after the signing treaties in 1894 with the then ruling Ugaas of Issa Somali, to established a protectorate in the region referred to as French Somaliland.

Most of the regional flora consists of African olive tree, Acacia tortilis with an added mixture of Buxus hildebrandtii, Tarchonanthus camphoratus, Terminalia brownie and the Flat top acacia, the mesquite tree, an invasive species from Central America, has become established.

Native fauna includes the Soemmerring's gazelle, Hamadryas baboon, Salt's dik-dik, Beira, African spurred tortoise, several species of Somali elephant shrew and Yellow-spotted rock hyrax, Somali ostrich, Black-backed jackal.

Average high temperatures are between 34 °C (93 °F) and 38 °C (100 °F) during summer months, and it can sometimes rise up to 41 °C (106 °F) during heat waves, and it can occasionally drop to below 27 °C (81 °F) at night.