It serves Amtrak's Pere Marquette line and is the central hub for Macatawa Area Express (MAX) buses.

The depot building is a renovated 1926 structure, built by the Pere Marquette Railroad.

The Pere Marquette ran night and day trains through the station from Chicago to points north and east.

Notable were the PM's Night Express from Chicago, which broke into two sections after Holland, one to Muskegon, another to Grand Rapids; and the seasonal Resort Special bound for Petoskey and Bay View.

[2] The Chesapeake and Ohio Railway continued service to Holland and Grand Rapids up to Amtrak's assuming passenger operations in 1971.