[7] In addition to her solo work, Herndon has been involved in numerous artistic collaborations, including projects with Iranian writer Reza Negarestani, Chicago-based producer Jlin and Dutch design studio Metahaven.

[4] As a teenager, she spent several years living in Berlin on a high school exchange program, absorbed in the city's dance[9] and techno scene.

[2] She studied under John Bischoff, James Fei, Maggi Payne, and Fred Frith, receiving her MFA in Electronic Music and Recording Media.

[2] Movement received a score of 8.1 on Pitchfork, who stated that Herndon "uses her crystalline voice as a chief input for her laptop, ultimately arriving at a poignant nexus of electronic accessibility and experimentation that owes as much to her academic forebears as her club contemporaries.

"[16] According to The Quietus, "Movement's sound certainly has its forebears and contemporaries – it's possible to detect traces of everyone from Coil and Aphex Twin to Ellen Allien and Laurel Halo in the mix – but equally it contains elements, both sonic and thematic, that are quite unlike any other electronic music currently out there.

Her rapid-punctuated, ethereal vocals... float above complex, dance music-inspired machinery, producing an effect that is arrestingly gorgeous and frightening all at once.

[8] The album explores a complicated relationship with technology,[22] and includes a track titled "Lonely at the Top" that is intended to trigger Autonomous sensory meridian response (ASMR).

[29] In 2015, Dryhurst and Herndon released an eleven minute long track called "Recruit", which they made for British menswear line Cottweiler.

[31] This collaborative work with Dryhurst and programmer Jules LaPlace involved a singing AI named Spawn, which they developed over the course of several years.

"[35][36] Holly+ is a method to decentralize Herndon's own identity, which enables a community of stewards to determine whether new media created with her voice should be co-sold in collaboration with Holly herself.

[37][36] In 2021, a real time version of Holly+ premiered at Sonar Festival in Barcelona, Spain in collaboration with Maria Arnal and Tarta Relena.

[46] Herndon contributed a composition titled "Relations" for artist Conrad Shawcross' installation, ADA, which was on view at the Palais de Tokyo in Paris, from February 4 to May 19, 2014.

[51] The exhibition, titled Everywhere and Nowhere, featured a combination of a 23.2-channel sound installation and related video works, as well as live performances by dancer and choreographer Jone San Martin, Jiu Jitsu fighter Sam Forsythe, and artist Brian Rogers.

[54] They set up a website called haveibeentrained.com, where artists can search the nearly 5.8 billion images in the Laion-5b dataset that is used to train AI art models Stable Diffusion and Midjourney.

[37] If an artist finds out that their work exists within the dataset, Spawning allows them to declare whether they want to continue or terminate the use of their imagery for AI training.

[37] In March 2023, Spawning, partnering with stock footage company Shutterstock and portfolio platform Artstation, announced that 80 million artworks have been opted out of Stable Diffusion V3 to honor artists' claims.