Holthees is a village in the former municipality of Boxmeer on the border of the Dutch provinces North Brabant and Limburg.

It is a composition of the German words hulta (wood) and hees (forest of thicket).

The Mariakapel (Mary Chapel) was built in the 15th century between Meppen castle and village.

The church was returned during the French occupation (early 19th century) and restored.

[4] Holthees used to provide military support during the defence of the Land of Cuijk Holthees forms a twin village with Smakt [nl], a village in the municipality of Venray in the province of Limburg.