The Holy Cross Crusaders women's basketball team is the women's basketball team that represents the College of the Holy Cross in Worcester, Massachusetts.

The Crusaders have appeared in the NCAA Women's Division I Basketball Championship 14 times.

The Crusaders have appeared in the Women's National Invitation Tournament (WNIT) twice.

The Crusaders have appeared in the Women's Basketball Invitational (WBI) once.

Holy Cross played in the Metro Atlantic Athletic Conference (MAAC) 1983 to 1990 before joining the Patriot League in 1990.