The cathedral is listed as a Belarusian Cultural heritage object and is considered one of the main landmarks in Minsk Upper city [ru].

[1] Before 1596 on the site of the Holy Spirit Cathedral was an Orthodox male monastery consecrated in the name of saints Cosmas and Damian.

The monastery also owned nearby lands on the eastern border of old Minsk and served as a military defense for the city.

Through the monastery it took over the entire city centre and destroyed many historical buildings and houses of common people.

[2][4] On May 3, 2022, a monument to Metropolitan Filaret was unveiled near the Holy Spirit Cathedral in Minsk.

[2] The iconostasis holds several important relics, of which the most valuable is Our Lady of Minsk (Icon) [be] from 1500.