In 2002, the seminary relocated to St Paschal's parish in Wavell Heights, and the building became the Brisbane campus of the Australian Catholic University.
The seminary serves the Catholic province of Queensland, covering the Cairns, Rockhampton, Townsville and Toowoomba dioceses as well as the Brisbane archdiocese.
Preaching at the dedication of the chapel, Cardinal Levada said "convestitum Spiritu Sancto" (clothed with the Holy Spirit) was more than a motto for the seminary.
"The church cannot operate without priests and the seminaries in Nigeria are extraordinarily dynamic, packed with 600 and 700 students," Father McCarthy said.
Monsignor Tony Randazzo, a former official of the Congregation for the Doctrine of the Faith, was appointed Rector of the seminary at the beginning of 2009.