Homer Le Grand Lyon (March 1, 1879 – May 31, 1956) was a U.S. Representative from North Carolina.

Born in Elizabethtown, North Carolina, Lyon attended the public schools, the Davis Military School, Winston, North Carolina, and the law department of the University of North Carolina at Chapel Hill.

He was admitted to the bar in 1900 and commenced practice in Whiteville, North Carolina.

He served as solicitor of the eighth judicial district of North Carolina 1913-1920.

He resumed the practice of law in Whiteville, North Carolina, until his retirement in 1950.