[5] For the 2012 model year, Honda removed the "Accord" prefix, making the name just "Crosstour", and gave its front grille a restyle.

[6][7] The Crosstour was sold in the United States, Canada, Mexico, China, Middle East, Southeast Asia and Russia.

On April 8, 2015, Honda announced that it was discontinuing production on the Crosstour at the end of the 2015 model year due to slow sales.

The Truth About Cars noted that the initial photos of the Honda Accord Crosstour posted on Facebook received a universally-negative reception with many describing it as "ugly", to which Honda responded with a “Message to Fans” claiming that "the two studio photos we posted didn’t give you enough detail, nor were they the best to showcase the vehicle" and that their "research suggests that the styling does test well among people shopping for a crossover".

[16][17] Some supporters suggested that the Crosstour was an inspiration for fastback (sloped backside) sedans such as the tenth-generation Honda Civic and Audi A7, although the latter two had better proportions all across.

[20][21][22] Honda's decision to initially offer the Crosstour in one trim, an EX-L V6 with the only options being all-wheel drive and navigation system, gave it a considerable higher price of entry than the competing Venza which offered numerous trims across a wide price range including a base four cylinder engine.