[4] South Texas Regional Airport at Hondo covers an area of 2,400 acres (971 ha) at an elevation of 930 feet (283 m) above mean sea level.

Two notable woman pilots, Betty Henrich and Hollywood stunt actress Mary Wiggins, were among the first WASPs to report for duty.

The aviation companies worked with the United States Air Force to screen pilots, and Universal Rundle manufactured bathroom products.

In the spring of 1973 the Air Force began a flight-screening program at Hondo using the T-41 Mescalero, a militarized version of the civilian Cessna 172.

After the mid-1970s the base housed a number of businesses, including a fiberglass-products plant, a greenhouse, a national guard armory, and the Medina Electric Cooperative.