Hong-Mei Xiao's career as an international soloist comprises critically acclaimed performances in major concert halls and with orchestras of great distinction throughout the world.

Her father, the renowned composer Xiao Heng,[5][6] provided her early violin training.

She continued her musical training with violist John Graham[7] in the United States, and received her Master of Music degree from the State University of New York at Stony Brook.

Hong-Mei Xiao has toured throughout Europe, North and South America, and Asia as a soloist, performing in major concert halls such as: She has appeared as a soloist with renowned orchestras including: Xiao’s playing style has been referred to by critics as masterful, spectacular, virtuosic, brilliant, expressive, energetic, intelligent, precise, and soulful.

Stylistic critiques include: Xiao's primary performance instrument is a viola made by Mantegazza in 1796 in Milan, Italy.