The Hongkong Canton & Macao Steamboat Company was a British merchant shipping and maritime trading company founded in 1865 in the Crown colony of Hong Kong.

The Hongkong Canton & Macao Steamboat Company was founded on 20 October 1865 in Hong Kong by a collection of people tied to the shipping industry in order to support the market for regional ferry transport in the Canton area.

China Navigation Company and the HCMSCo had entered into a collaboration to jointly carry out business in the area which continued into the early 1900s.

[5] With the opening of the West River Trade in 1897, HCMSCo together with the China Navigation Company and Jardine Matheson's Indo-China Steam Navigation Company, partnered together to open the new trade which became active from around 1897 to 1917 following the opening of several Treaty Ports like Wuzhou, Sanshui and Jiangmen to foreign trade in 1897.

The West River trade declined with the advent of the Kowloon Canton Railway.