Niko is married to Sarah (Jeanette Hain), but their marriage is in danger because his wife has a romance with her boss Serge (Jan Josef Liefers).

Niko now believes that moving his father to a retirement home has become inevitable, however his daughter Tilda does not think that this is the way Amandus should be treated.

Tilda is told by her paediatrician Dr. Ehlers (Tilo Prückner) that visiting places the sick person knows well can help living with the disease.

In the evening, the janitor Erdal (Fahri Yardim) finds them and helps the two continue their journey to Venice.

Going by a sheep lorry, they get stopped by the police but manage to flee before they get caught, and find shelter in a monastery.

Amandus spends his remaining days contently with his family, and dies of cardiac failure in Tilda's presence.

[1] On 21 March 2018, German media announced that Til Schweiger would create a remake of Honig im Kopf – with its literally-translated name, Honey in the Head – for the US market, with him as director and with Nick Nolte and Matt Dillon as main cast members.