He attended the New Roads All-age School, Cornwall College, and the University of the West Indies.

[1] Trained a medical doctor, Chang entered politics in 1976 as a member of the Jamaica Labour Party (JLP).

He was a youth leader in East Rural St. Andrew and the vice-president of Young Jamaica.

From 2007 to 2011, Chang served as Minister of Housing, Environment, Water and Local Government.

[2] In January 2020, the Quebec Avenue roadway in Montego Bay was renamed to Dr Horace Chang Boulevard.