The history of Horne Church is inextricably tied to Hvedholm Manor, located about 2 km (1.2 mi) to the south and to the noble family Brahe associated with that estate.

The alignment of these later extensions was not quite set at 180 degrees,[2] so that the resulting central interior aisle does not split the congregation pews evenly, and the traditional women's side is more spacious than the men's.

There are three interesting and delicately designed weather vanes atop the church, one at the apex of each of the vaulted circular towers, but each at a different height.

The pulpit, of French Empire influence, is situated within the central round original church because of the elongated congregation seating.

Horne Church is situated in a countryside of gently rolling hills, most of which is utilized for grain cultivation and cattle grazing.

It sits atop a knoll at the north side of the village of Horne, and it is quite visible from many aspects for up to 5 km (3.1 mi) from certain vantage points.