With its collection of churches, chapels and tombs, Horomos has been described as one of the most significant spiritual and cultural religious centers in medieval Armenia and one of the largest in all the Christian East.

John, Minas, and George, a series of large halls (gavits), a triumphal arch, and various smaller chapels and mausolea.

[3] The Church of Saint John ("Surb-Yovannēs"), now in a highly ruined state, was built by King Yovhannēs-Smbat, son of Gagik I of Armenia, in 1038, according to an inscription.

[9] The main chamber is decorated by a three-arris vault supported by four columns, and an eastern wall adorned with four khatchkar crosses.

[10] The mausoleum is a square space of about 8x8 meters, lined with blind arcades supporting a huge "stone tent" structure of the type of the stalactite vaults.

[10] A dedicatory inscription appears on the tympanum: By the grace of Christ, I, Vacë, son of Sargis, and my wife Mamaxatun, daughter of Abuserh, we built this hall of relics in this monastery of Horomos, under the prelature of Ter Barsel, son of Amir Erkat', and we gave in present at the library the vineyard that we had bought in Awsakan, for the office and for the relic.

[13] His inscription in this mausoleum reads: In the year 726 (ie 1277), by the will of God, I, Aṙwic Hogew[oreanc'], son of Sargis, and my wife Seda, we built from our fair income this reliquary room, at the door of our zhamatun, for the memory of our parents and... [I have compl]eted this by the power of God, master Frer, (originally) from Karnoy K'alak'.The monastery was active in the creation of manuscripts.

[14][15] In one of the pages, entitled ""Entry into Jerusalem", Jesus, riding a donkey, is actually shown entering the gates of Horomos Monastery itself.

[16] The monastery continued to function after the fall of Ani, but appears to have been temporary abandoned in the early 17th century and then reoccupied and repaired in 1685.