Housed in the Art Nouveau interiors is a permanent display of furniture, utensils and art objects designed by Horta and his contemporaries, as well as documents related to his life and time.

The museum also organises temporary exhibitions on topics related to Horta and his art.

[2] The UNESCO commission recognised the Horta Museum as UNESCO World Heritage in 2000, as part of the listing 'Major Town Houses of the Architect Victor Horta': The four major town houses—Hôtel Tassel, Hôtel Solvay, Hôtel van Eetvelde, and Maison & Atelier Horta—located in Brussels and designed by the architect Victor Horta, one of the earliest initiators of Art Nouveau, are some of the most remarkable pioneering works of architecture of the end of the 19th century.

The stylistic revolution represented by these works is characterised by their open plan, the diffusion of light, and the brilliant joining of the curved lines of decoration with the structure of the building.

In 2014, it won the European Union Prize for Cultural Heritage / Europa Nostra Award.