Hosam Aiesh (Arabic: حُسَام عَايِش, Husâm Âyiş, born 14 April 1995) is a former professional footballer who played as a right winger.

After spending a season on loan at the Varbergs BolS in 2014, he joined Östersunds FK on 1 January 2015 on a free transfer.

In 2017, Aiesh managed to win his first major trophy, the 2017 Svenska Cupen, after Östersund defeated IFK Norrköping 4–1 in the final, as a result of the victory, also qualifying for the 2017–18 UEFA Europa League, marking their first appearance in a European competition tournament.

Östersund earned a shock 2–0 victory against Turkish giants Galatasaray at the Jämtkraft Arena and eliminated them after a 1–1 draw in Istanbul.

On 1 February 2022, Aiesh debuted for Syria in a 2–0 loss to South Korea in qualification towards the 2022 FIFA World Cup entering the match as a substitute in the 60th minute for Amro Jenyat.