In 1999 the gallery moved to a 5,000-square-foot (460 m2) space in San Francisco's South of Market neighborhood on 430 Clementina Street.
Designed in 1999 by Fougeron Architecture and Endres Ware Engineers, the architect was awarded for her work on the space.
[4] Hosfelt Gallery was among the first to exhibit such critically acclaimed artists as Shahzia Sikander,[5] Stefan Kürten,[6] Shirin Neshat,[7] Marco Maggi[8] and Jim Campbell.
[10] Hosfelt Gallery represents emerging to established local and international contemporary artists, including: Jim Campbell, Russell Crotty, Isabella Kirkland, Stefan Kürten, Michael Light, Marco Maggi, John O'Reilly, Liliana Porter, Alan Rath and William T.
These include Chris Ballantyne, Rina Banerjee, Julie Chang, Reed Danziger, Anoka Faruqee, Jutta Haeckel, Emil Lukas, Driss Ouadahi, Lordy Rodriguez, Gideon Rubin and Andrew Schoultz.