It is located on Avenida Ortega y Gasset Ensanche La Fe, Santo Domingo, Distrito Nacional of the Dominican Republic.

Under the supervision of the Board, the HGPS has an organizational structure headed by the Executive Directorate, responsible for coordinating the planning and management to achieve its goals.

The HGPS receives a grant from the Dominican Government that covers the annual cost of exemptions and discounts to patients with limited resources.

Law 163-03, dated February 10, 2003, approved the grant contract between the Dominican State and the Boards of both HGPS and CEDIMAT for the assignment and transfer of land of the Plaza de la Salud.

Since its inception, the HGPS has been perceived by the Dominican people as being a State-run facility that should offer free services as it was initially built using State funds.