Houben-Weyl Methods of Organic Chemistry (Ger.
Methoden der Organischen Chemie) established in 1909 by the German chemist Theodor Weyl, is a classic chemistry text.
It consisted initially of two volumes and covered literature published as early as 1834.
It is considered one of the most significant resources for chemists.
[1] A new English-language edition was published by Thieme from 2000 to 2010 as Science of Synthesis in 48 volumes.