House of Cosbys is an American animated sitcom created by Justin Roiland for the film festival Channel 101.

The series centers on Mitchell Reynolds (Jeff Davis), who builds a cloning machine to make duplicates of his favorite comedian, Bill Cosby.

Many participants of Channel 101 gave voices to the series, including Rob Schrab, Steve Agee, and all three members of The Lonely Island.

He and his close friends, Sevan Najarian and Abed Gheith, were more interested in creating comedic short films, and would work on them at his apartment in spare time.

While the original idea was similar in setup to the sitcom The Brady Bunch—consisting of multiple Cosbys together in a home—it eventually evolved into its final form with more development.

Following this, a "perfect storm" of things helped lead to the ending of the series: Roiland had a close friend die in a car accident, which was "traumatizing" for him, he and his small team grew exhausted with making the series, and he and Channel 101's site administrator Dan Harmon received a cease and desist letter from Bill Cosby's attorney in June 2005: Dear sirs, we are lawyers for Mr. William H Cosby, Jr. We have just learned that you offer a deeply offensive animated film that you created, entitled House of Cosbys.

[...] Therefore, we demand that you immediately cease and desist from any use of our client's name, voice, and likeness, including the development and distribution of the House of Cosbys series.

He gave the script to friends Chester Tam, and Chris Romano and Eric Falconer, who produced an "unofficial" fifth episode of House of Cosbys.

"[6] Blogger Andy Baio made the series available via his website, waxy.org, beginning in November 2005, though he was also sent a letter from Cosby's attorney the following March.