The house is famous for its eccentric fashions, the use of Surrealism in its collections, its sense of humour, the "shocking Pink" color, gender crossing, and its use of human anatomy depictions, among other unconventional themes.

[10] In 2014, the house presented its first clothes collection since 1954 under Zanini, and re-established its boutique at 21 Place Vendôme, on the first floor of the building which Elsa Schiaparelli bought from Louise Chéruit in 1935.

In December 2020, Kim Kardashian posted images to Instagram of herself wearing a green bodice with prominently sculpted abdominal muscles and large, bauble-like black and gold earrings, all designed by Schiaparelli.

[21] In January, singer Lady Gaga wore a Schiaparelli ball gown decorated with a golden dove of peace to the inauguration of Joe Biden, where she performed the national anthem.

[22] The New York Times and Harper's Bazaar praised Schiaparelli as a breakout star of the 63rd Annual Grammy Awards, for which they dressed Beyoncé and Noah Cyrus.

[22][23] For the Spring Summer 2023 Haute Couture collection, the brand produced a series of gowns featuring shockingly lifelike 3D embroidery of animal heads such as a wolf, a leopard, and a lion notably worn by Kylie Jenner.

The realism of the garments sparked fierce debate online among animal rights activists, however the pieces were constructed out of resin, foam, silk, and other non-fur materials.