[2] The house was originally constructed by Gerónimo de Aguilar in 1524 and is located on the outer edge of what was the sacred precinct of the Templo Mayor prior to the Conquest.

[3] After receiving permission from Spanish king Carlos V and the archbishop of Mexico City, Juan de Zumárraga had a printing press brought from Europe in 1539.

[6] One of these documents was a catechism entitled Breve y más compendiosa doctrina christiana en lengua mexicana y castellana ("The Brief and Most Concise Christian Doctrine in the Mexican Language") written by the archbishop himself.

In the 20th century, the building was mostly used for offices, including being the home to a paper and printing services operation called the "Imprenta y Papelería Militar 'Marte'."

[3] Today, the house serves as the Continuing Education Center for UAM with various exhibition rooms, a bookstore and facilities for conferences and courses.