Houstonia is a city in northwest Pettis County, Missouri, United States.

Buffalo Creek flows past the east side of the community.

[8] According to the United States Census Bureau, the city has a total area of 0.20 square miles (0.52 km2), all land.

24.4% of all households were made up of individuals, and 9.8% had someone living alone who was 65 years of age or older.

The racial makeup of the city was 97.09% White, 1.09% African American, 1.09% Asian, and 0.73% from two or more races.

22.2% of all households were made up of individuals, and 14.1% had someone living alone who was 65 years of age or older.

About 20.8% of families and 24.7% of the population were below the poverty line, including 24.7% of those under the age of eighteen and 16.7% of those 65 or over.