Hsueh Jui-yuan (Chinese: 薛瑞元; pinyin: Xuē Ruìyuán; born June 1955) is a Taiwanese physician who has served as the vice minister of Health and Welfare since August 2017 until July 18, 2022.

Hsueh completed his degree in medicine from Taipei Medical University in 1980.

He then obtained his bachelor's and master's degree in law from National Taiwan University in 1997 and 2001, respectively.

In 2008–2015, he was the deputy superintendent of Shuang Ho Hospital of Taipei Medical University.

Hsueh succeeded Chen Shih-chung as Minister of Health and Welfare on July 18, 2022.