After Looser had earned his MBA from Columbia University New York,[2] he joined his parents company in 1964 and was responsible for the establishment and leadership of the ELCO Group in France, Belgium and Luxembourg until 1980.

[2] During his stay in Paris in 1957 to learn the language, posters from an Impressionist exhibition made a big impression on him and he went to museums around the world whenever he had the time.

In his twenties, Looser completed various study trips during his training period to Mexico, Japan, Paris, London or New York and laid the foundation of his passion for collecting art.

The museum-suitable works of the collection were introduced in 2008 to the Fondation Hubert Looser, which makes this cultural asset available to the public as a permanent exhibition at the Kunsthaus Zürich.

[5] On 9 October 2021, some pieces from Looser's collection, including works by Cy Twombly, Jackson Pollock, Ellsworth Kelly, and Agnes Martin, were moved into the new annex of the Kunsthaus Zürich.