[5] In 1958, Archbishop Thomas Boland announced a campaign to build additional high schools throughout the four counties of the Archdiocese of Newark.

In the eighteenth century the site was the home of Jane Tuers, a member of the Van Rypen family and an American Revolutionary War heroine.

[8] A campaign was started to save Hudson Catholic Regional High School led by current students, alumni, faculty, and the surrounding community.

The Brothers of the Christian Schools, as St. John Baptist de la Salle's followers came to be known, live in a prayerful community in a residence on campus.

Accelerated content, in-depth study, small group discussion, interdisciplinary approaches and experimental learning opportunities are integral parts of the Scholars Program.

Eighth grade students who select Hudson Catholic Regional High School as one of their choices for secondary education and who meet the criteria will be invited to join the Scholars Program.

[18] The Hawks also won Hudson County Interscholastic Athletic Association League in 2011, 2012, The Hudson Catholic hockey team won the parochial state hockey championship in 2000, defeating Seton Hall Preparatory School by a score of 2–1, and then defeated Bayonne High School by a 4–2 margin to win the Tournament of Champions.

[21] In 2013, the baseball team won its first state title, finishing the season with a 19–10 record and defeating St. Joseph High School by a score of 7–0 in the Non-Public B tournament championship game.

[23] The boys soccer team won the Non-Public B North state sectional final against Montclair Kimberley Academy in a 1-0 victory in 2016.

The girls basketball team won the Hudson County Tournament in 2018 defeating Bayonne High School by a score of 55-42.

[citation needed] The girls volleyball team won the Hudson County Tournament in 2015 defeating Secaucus High School by a score of 2-1.

[citation needed] The 2016 softball team won the Hudson County Tournament, the program's first, defeating Kearny High School in the championship gameby a score of 15-0.

In addition to the various catalogs, brochures, and viewbooks that are available, the room is equipped with high-speed cable Internet which enables the students to take virtual tours of college campuses, as well as apply on-line when applicable.

The counselors coordinate school programs and events such as the SAT's, college fairs, career days, financial aid seminars and study skills workshops.