Like some other actors of English Renaissance theatre, Clark began as a boy player filling female roles.
He played Gratiana in Shirley's The Wedding in 1626, and Bess Bridges in both parts of Heywood's The Fair Maid of the West in 1630–31.
Clark, like some other members of the troupe, disappears from the available records in 1637 and 1638; he may have been one of several actors from the company who travelled with James Shirley to Dublin to work at the Werburgh Street Theatre.
[2] By 1639, however, Clark was back in London and a member of the King's Men; he appeared in their revival of The Custom of the Country in that year.
He was also involved in the January 1648 attempt to revive the company (which failed by the summer of that year, when the actors missed a payment due), despite the fact that the theatres had been closed by the Puritan regime of the English Commonwealth.