Hugh I of Chalon-Arlay (1288–1322) was lord of Arlay and of Vitteaux, and belonged to the house of Chalon-Arlay.

He was the son of lord John I of Chalon-Arlay and his first wife Marguerite of Burgundy (daughter of duke Hugh IV of Burgundy), and his grandfather John, Count of Chalon was count-regent from the death of Otto III, count of Burgundy onwards.

On 13 February 1302 Hugh I married Béatrice de La Tour-du-Pin (1275–1347) (daughter of count Humbert I of Viennois).

They had one child