Hughesville is a census-designated place (CDP) in Charles County, Maryland, United States.

[5] Because Hughesville, though small, is considered the strategic geographic center of the tri-county Southern Maryland region,[citation needed] it houses institutions such as the headquarters for the Southern Maryland Electric Cooperative, an animal shelter, an economic development council, a board of realtors, and a homeless women's shelter, which serve the tri-county area.

The town has no traditional grid-layout streets, but consists of merely businesses along the highway and some very small outlying housing developments.

[6] A 5.5-MW solar farm near Hughesville generates enough power for 600 homes, and offsets the pollution of 1,600 cars.

"Hughesville: A Commercial and Tobacco Marketing Center" Charles County Historic Preservation Magazine https://www.charlescountymd.gov/Home/ShowDocument?id=3581