In 2013, she defended a doctoral thesis, directed by Professor Georges Barakat, at the Le Havre Normandy University on permanent magnet synchronous machines and their practical applications for wind energy.

Tiegna joined La République en Marche, a party created by Emmanuel Macron, shortly after its founding in 2016.

In March 2018, Huguette Tiegna presented a report that she conducted as part of the work of the Parliamentary Office for the Evaluation of Scientific and Technological Choices (OPECST) on the issues and applications of 3D printing.

During the same month, Tiegna was asked by OPECST to conduct a mission, "Cap 2040" on stopping the sale of vehicles emitting greenhouse gases by 2040.

In parliament, Tiegna serves on the Committee on Economic Affairs[2] and the Parliamentary Office for the Evaluation of Scientific and Technological Choices (OPECST).