[2] The largest localities (cities, towns, and villages) are:[3] During the Prehispanic era, Huitzilac was a part of the domain of Cuahanahuac (Cuernavaca).

The town was an important stagecoach stop on the route from Mexico City to Cuernavaca, but this changed with the construction of the railroad in 1897. huitzilac (Dec 14, 2018) During the Revolution, General Genovevo de la O fought against the government.

Huitizlac was burned in April 1912, and de la O was able to mobilize 4,000 men plus artillery to join in the fight to liberate Cuernavaca.

Thanks to the popularity of the Ejército Libertador del Sur in this region, Huitizalc and Santa María Ahuacatitlán were able to forget their old rivalries.

Iron crosses have been erected at Km 47 of the federal Mexico City-Cuernavaca highway to commemorate Francisco R. Serrano and his associates, Daniel and Miguel A. Peralta, Carlos Ariza, Carlos Vidal, Rafael Martínez de Escobar, Cecilio González, Enrique Monteverde, Alonso Capetillo Robles, Augusto Peña, Antonio Jáuregui, José Valle Arce, Octavio Almada, and Ernesto Noriega Méndez.

[8] Toxic medical waste was found at Km 49 of the Mexican Federal Highway 95D near the monument to Josė María Morelos y Pavón in Tres Marias; four toll collectors who work for Federal Roads and Bridges and Related Services, (CAPUFE) in Morelos have died from the coronavirus.

[11] The most important festival in Huitzilac is celebrated on March 19, in honor of the town's patron saint, San José.

An image of St. Joseph disappeared from the church during the Mexican Revolution and was recovered on September 1, 1921, so there is a festival to remember this event.