She is known for her roles in dramas Nail Polish, Kankar, Jab We Wed and Sammi.
[3] She made her debut as an actress on the hit PTV drama serial Jhok Siyal, playing a lead role along with Abid Ali, whom she later married.
[4] Since then she has appeared in numerous dramas, including Akbari Asghari, Sabz Pari Laal Kabootar, Nail Polish, Kankar, Jab We Wed, Ranjish Hi Sahi and Sammi.
[5] Humaira also sang songs in Jhok Sial and in the dramas directed by her husband Abid.
[10][11] She and Abid Ali divorced in 2006; she still uses his last name and both remained on good terms until his death in 2019.