Huseyngulu Khan Khoyski (Azerbaijani: Hüseynqulu xan Xoyski; September 22, 1870, in Yelisavetpol (modern-day Ganja), Elizavetpol Governorate, Russian Empire – 1955, in Istanbul, Turkey) was Major general of the Russian Imperial Army, elder brother of the Prime Minister of the Democratic Republic of Azerbaijan Fatali khan Khoyski.

[2][3] His great grandfather Jafar Qoli, the Khan of Khoy was defeated by the Iranian Fath-Ali Shah and with his 20,000 army retreated to Echmiadzin.

During the period of independence of the Azerbaijan Democratic Republic, he became deputy governor-general of Ganja, Khudadat-bey Rafibekov.

After the occupation of Azerbaijan by the Bolsheviks, he took with him his wife Shirinbeyim Khanym (she was the daughter of a descendant of the Ganja Khan Javad Khan,[5] the daughter of Valiyya, the 6-month-old grandson of Abbas and the son-in-law of Colonel Jahangir bey Kazimbeyli, who headed uprising and left for Qajar Iran, and from there to Turkey.

His younger brother Fatali Khan Khoyski was one of the founders and prime ministers of the Democratic Republic of Azerbaijan.