He appeared as Takashi Nozoe in the 2019 film Sora no Restaurant, and as Kamiya Yusuke in the TV drama series Hidarikiki no Eren.

[6] He debut as a solo artist on July 25, 2012 with the mini album Dai-san Wakusei Kōkyōkyoku after appearing in a live show by Rake (singer) that year.

[7] The album's songs were based on his feelings about real life events such as the 2011 Great East Japan earthquake.

[9] He released his single "Yakan Hikō on June 5, 2013, which served as the ending theme song for the Japanese drama series Minna!

The album's title, which literally means "Eve of Independence", is a reference to his decision to become a solo artist.

[15] On April 2, 2014, he released his second mini album, Dakara Carnation wa Sukidenai, which was about his feelings for his mother.

[21] He made his stage debut in June, in the play Kanojo no Kigen by the Gekidan Shikagoroshi Theater Company [ja].

[22] On September 4, he released his song "Otamajakushi", which served as the opening theme of the film version of Minna!

[27][28] On August 27, he released his single "Pino to Amélie", which served as the second ending theme of the 21st season of the anime Naruto: Shippuden.

[32] On March 28, 2018, he released Huwie's Best, a compilation album of his fans' favorite songs as selected through online voting.

[33] In December 2018, he performed "Encore" which served as the theme song for the 2018 drama series Heisei Bashiru [ja] and in which he had a cameo.

[34] He also performed "Anata wa Doko ni Iruno" which served as the theme song of the 2019 drama series Sasurai Onsen Endō Ken'ichi [ja] in which he also had a cameo as a Kokeshi doll craftsman.

[42] In 2020, he performed the second ending theme of the anime Case File nº221: Kabukicho entitled "Parade", with lyrics about Ishizaki's loneliness.

[48] In 2021, he performed the theme song "Ayame" of the 5th season of the TV drama series Keishichō - Sōsaikkachō [ja].

[49][50] In February, he performed a cover of "Sayonara Elergy", a song he wrote originally forMasaki Suda, on The First Take YouTube channel.

[52] He performed "Black Star" which served as the theme song of the film Watashi wa Hakuchō.

[66] On November 27, he released his sixth album, "night milk", featuring his cover of songs by Fujii Kaze, Mrs. Green Apple and others.

"[70] Hirokazu Suzuki of RealSound said that the "core" of his expression is "real" adding that he writes "beautiful songs", but he does not sing "pretty words".

[59] Ishizaki describes himself as "a sloppy person who does not understand other people's feelings, but he is deeply aware that he lives his life with the support of others".