Hyoscyameae is an Old World tribe of the subfamily Solanoideae of the flowering plant family Solanaceae.

All seven genera of the tribe are poisonous and have a long tradition of use as medicinal plants, being rich in tropane alkaloids with anticholinergic properties.

[2] Furthermore, the genera Atropa, Hyoscyamus, Scopolia and Physochlaina have furnished entheogens - the first three in the historical context of European witchcraft and, more specifically, of the flying ointments employed in such practices,[3] while the similar chemistry of the remaining genera points to the potential for entheogenic use.

Six of the genera have dry, pyxidial fruits i.e. capsules dehiscing by an operculum and thus resembling a pot with a lid.

The late Professor Armando Theodoro Hunziker, one of the foremost authorities on the Solanaceae, was of the opinion that Pauia should be subsumed in Atropa.