Yellow canthal–dorsolateral lines with well-defined edges are typically present; often, they have a thin black outline.

[3] The male advertisement call is a harsh "creak", with occasional longer, pulsatile "croaks".

[3] Hyperolius semidiscus inhabits savanna and thickets typically at low elevations, but occasionally even higher 1,000 m (3,300 ft).

It is an uncommon species that is locally adversely affected by afforestation, agriculture, and urban spread.

However, it might be benefiting from the spread of the invasive water hyacinth that creates suitable breeding habitat.