[1] He studied law and worked as a clerk for the Ottoman Empire before the Albanian Declaration of Independence.

[2] He was part of the delegation that went to Neuwied, Germany in 1914, to offer the Albanian crown to Prince Wilhelm of Wied.

Vrioni was elected as representative of Berat in Albanian Parliament of 1932, reelected again in 1937.

Hysen Vrioni is remembered for the First Pact of Tirana on November 27, 1926, which he signed on behalf of Ahmet Zogu, while Baron Pompeo Aloisi signed for the Italian side.

[4] The Albanian left-wing leader and bishop Fan Noli had a low opinion on him considering Vrioni's feudal and Ottoman background and his loyalty to Ahmet Zogu, proclaimed King of Albania in 1925.