Produced by the former, it was released in late 2005 and peaked at number five on the Billboard Hot 100 chart, making it T-Pain's second top ten single, and Mike Jones's first.

The official remix of the song features Twista, Pimp C, R. Kelly, Too Short, Paul Wall and MJG, and was accompanied with its own music video.

[2] T-Pain said during a USA Today interview that "I'm 'n Luv (wit a Stripper)" was inspired by a night when the singer took his friend to a strip club for the first time.

It utilizes a steel string acoustic guitar, hip hop drum machine, and a chiptune synthesizer known as "Future Flute".

[4] The original version of the music video appeared on MTV but was quickly removed due to strong sexual content.

The song is parodied by "Weird Al" Yankovic with "I'm 'n Luv wit the Skipper" during his Straight Outta Lynwood Tour.